DAIT-Funded Research Publications


* indicates a link to a contract summary
Contract ID Contract Title Authors Program Name Contract Principal Investigator
HHSN266200400067C * An approach to incorporate linkage disequilibrium structure into genomic association analysis Fengyu Zhang, Diane Wagener Population Genetics Analysis Program Diane Wagener
  Minimizing back exchange in 18O/16O quantitative proteomics experiments by incorporation of immobilized trypsin into the initial digestion step. Joel R Sevinsky, Kristy J Brown, Benjamin J Cargile, Jonathan L Bundy, James L Stephenson Population Genetics Analysis Program Diane Wagener
  Signatures of natural selection are not uniform across genes of innate immune system, but purifying selection is the dominant signature. Souvik Mukherjeea, Neeta Sarkar-Roya, Diane K. Wagener and Partha P. Majumder Population Genetics Analysis Program Diane Wagener
  A Comprehensive Defensin Assay for Human Saliva. Michael S. Gardner, Megan D. Rowland, Amy Y. Siu, Jonathan L. Bundy, Diane K. Wagener and James L. Stephenson, Jr. Population Genetics Analysis Program Diane Wagener
  Systematic Comparison of the Human Saliva and Plasma Proteomes. Yan, W., Apweiler, R., Balgley, B.M., Boontheung, P., Bundy, J.L., Cargile, B.J., Cole, S., Fang, X., Gonzalez-Begne, M., Griffin, T.J., Hagen, F., Hu, S., Lee, C.S., Malamud, D., Melvin, J.E., Menon, R., Mueller, M., Qiao, R., Rhodus, N.L., Sevinsky, J.R., States, D., Stephenson, Jr., J.L., Than, S., Yates, III, J.R., Yu, W., Xie, H., Xie, Y., Omenn, G.S., Loo, J.A., Wong, D.T. (2009) Population Genetics Analysis Program Diane Wagener
  Signatures of natural selection are not uniform across genes of innate immune system, but purifying selection is the dominant signature. Souvik Mukherjeea, Neeta Sarkar-Roya, Diane K. Wagener and Partha P. Majumder Population Genetics Analysis Program Diane Wagener
  Prediction of the Isoelectric Point of Tryptic Peptides Based on Adjacent Amino Acid Effects Benjamin J. Cargile, Joel R. Sevinsky, Amal S. Essader, James L. Stephenson, Jr., and Jonathan L. Bundy Population Genetics Analysis Program Diane Wagener
  GEQUEST: Using Peptide Isoelectric Point, Accurate Mass, and Tandem Mass Spectrometry to Search Genome Sequences Joel R. Sevinsky, Benjamin J. Cargile, Maureen K. Bunger, Fanyu Meng, Nathan A. Yates, Ronald C. Hendrickson and James L. Stephenson, Jr. Population Genetics Analysis Program Diane Wagener
  Minimizing Back Exchange in 18O/16O Quantitative Proteomics Experiments by Incorporation of Immobilized Trypsin into the Initial Digestion Step Sevinsky, J.R., Brown, K.J., Cargile, B.J., Bundy, J.L., Stephenson, J.L. Jr. Population Genetics Analysis Program Diane Wagener
HHSN266200400064C* Lessons from the past: Familial aggregation analysis of fatal pandemic influenza (Spanish flu) in Iceland in 1918 Magnus Gottfredsson, Bjarni V. Halldorsson, Stefan Jonsson, Mar Kristjansson, Kristleifur Kristjansson, Karl G. Kristinsson, Arthur Love, Thorsteinn Blondal, Cecile Viboud, Sverrir Thorvaldsson, Agnar Helgason, Jeffrey R. Gulcher, K?ri Stefansson, and Ingileif Jonsdottir Population Genetics Analysis Program Jeff Gulcher
HHSN266200400065C* T cell epitope discovery for variola and vaccinia viruses. Kennedy RB, Poland GA. Population Genetics Analysis Program Gregory Poland
  Mass spectrometry and peptide-based vaccine development. Ovsyannikova IG, Johnson KL, Bergen HR III, Poland GA. Population Genetics Analysis Program Gregory Poland
  Pharmacology, vaccinomics, and the second golden age of vaccinology. Poland GA Population Genetics Analysis Program Gregory Poland
  Vaccines for Biodefense and Emerging and Neglected Diseases Poland GA, Kennedy RB. Population Genetics Analysis Program Gregory Poland
  Response surface methodology to determine optimal cytokine responses in human peripheral blood mononuclear cells ELISA after smallpox vaccination. Ryan JE, Dhiman N, Ovsyannikova IG, Vierkant RA, Pankratz VS, Poland GA. Population Genetics Analysis Program Gregory Poland
  Gender effects on humoral immune responses to smallpox vaccine. Kennedy RB, Ovsyannikova IG, Pankratz VS, Vierkant RA, Jacobson RM, Ryan MAK, Poland GA. Population Genetics Analysis Program Gregory Poland
  Discovery of naturally processed and HLA presented Class I peptides from vaccinia virus using mass spectrometry for vaccine development. Johnson KL, Ovsyannikova IG, Mason CJ, Bergen HR III, Poland GA. Population Genetics Analysis Program Gregory Poland
  Statistical approach to estimate vaccinia-specific neutralizing antibody titers using a high throughput assay. Kennedy RB, Pankratz VS, Golding H, Poland GA. Population Genetics Analysis Program Gregory Poland
  The immunology of smallpox vaccines. Kennedy RB, Ovsyannikova IG, Jacobson RM, Poland GA. Population Genetics Analysis Program Gregory Poland
  Adversomics: The emerging field of vaccine adverse event immunogenetics. Poland GA, Ovsyannikova IG, Jacobson RM. Population Genetics Analysis Program Gregory Poland
  Next-generation sequencing: a transformative tool for vaccinology. Dhiman N, Smith DI, Poland GA. Population Genetics Analysis Program Gregory Poland
  Application of pharmacogenomics to vaccines. Poland GA, Ovsyannikova IG, Jacobson RM. Population Genetics Analysis Program Gregory Poland
HHSN266200400066C* Interferon and Interferon-Induced Chemokine Expression Is Associated with Control of Acute Viremia in West Nile Virus-Infected Blood Donors Leslie H. Tobler, Mark J. Cameron, Marion C. Lanteri, Harry E. Prince, Ali Danesh, Desmond Persad, Robert S. Lanciotti, Philip J. Norris, David J. Kelvin, and Michael P. Busch, Blood Systems Research Institute and Departments of Medicine and Laboratory Medicine, University of California, San Francisco, and Focus Diagnostics, Cypress, California; Arbovirus Disease Branch, Centers for Disease Control and Prevention, Fort Collins, Colorado; and University Health Network, Toronto, Canada Population Genetics Analysis Program Mark Loeb
  Epitope discovery in West Nile virus infection: Identification and immune recognition of viral epitopes. McMurtrey, C., Lelic, A., Piazza, P., Chakrabarti, A.K., Yablonski, E.J., Wahl, A., Bardet, W., Eckerd, A., Cook, R.I., Buchli, R., Loeb, M., Rinaldo, C.R., Bramson, J., and Hildebrand, W.H. Population Genetics Analysis Program Mark Loeb
  The Memory T cell Response to West Nile Virus in Symptomatic Humans Following Natural Infection is not Influenced by Age and is Dominated by a Restricted Set of CD8+ T Cell Epitopes. Parsons, R., Lelic, A., Hayes, L., Carter, A., Marshall, L., Evelegh, C., McMurtrey, C., Hildebrand, W., Loeb, M. and Bramson, J.L Population Genetics Analysis Program Mark Loeb
  A novel computer algorithm improves antibody epitope prediction using affinity-selected mimotopes: A case study using monoclonal antibodies against the West Nile virus E protein. Denisova, G.F., Denisov, D.A., Yeung, J., Loeb, M., Diamond, M.S., and Bramson, J.L. Population Genetics Analysis Program Mark Loeb
  Deciphering epitope specificities within polyserum using affinity selection of random peptides and a novel algorithm based on pattern recognition theory Denisov, D.A., Denisova, G.F, Lelic, A., Loeb, M., and Bramson, J.L. Population Genetics Analysis Program Mark Loeb
HHSN266200400068C* Capturing the Spectrum of Interaction Effects in Genetic Association Studies by Simulated Evaporative Cooling Network Analysis Brett A. McKinney, James E. Crowe, Jr, Jingyu Guo, Dehua Tian Population Genetics Analysis Program Richard Kaslow
1 U01 AI067068-01* High-throughput killer cell immunoglobulin-like receptor genotyping by MALDI-TOF mass spectrometry with discovery of novel alleles Kathleen A. Houtchens, Robert J. Nichols, Martha B. Ladner, Hannah E. Boal, Cristina Sollars, Daniel E. Geraghty, Lee M. Davis, Peter Parham and Elizabeth A. Trachtenberg HLA Region Genetics in Immune-mediated Diseases Henry Erlich
1 U01 AI069197-01* Risk assessment in haematopoietic stem cell transplantation: histocompatibility. Petersdorf EW. HLA Region Genetics in Immune-mediated Diseases Effie Petersdorf
  Immunogenomics of unrelated hematopoietic cell transplantation Effie W Petersdorf HLA Region Genetics in Immune-mediated Diseases Effie Petersdorf
  Clinical importance of HLA-DPB1 in haematopoietic cell transplantation B E Shaw, T Gooley, J A Madrigal, M Malkki, S G E Marsh, E W Petersdorf HLA Region Genetics in Immune-mediated Diseases Effie Petersdorf
  Clinical significance of donor-recipient HLA matching on survival after myeloablative hematopoietic cell transplantation from unrelated donors E. W. Petersdorf , T. Gooley , M. Malkki & M. Horowitz HLA Region Genetics in Immune-mediated Diseases Effie Petersdorf
1 U19 AI067152-01* Risk alleles for multiple sclerosis identified by a genomewide study. International Multiple Sclerosis Genetics Consortium, Hafler DA, Compston A, Sawcer S, Lander ES, Daly MJ, De Jager PL, de Bakker PI, Gabriel SB, Mirel DB, Ivinson AJ, Pericak-Vance MA, Gregory SG, Rioux JD, McCauley JL, Haines JL, Barcellos LF, Cree B, Oksenberg JR, Hauser SL. HLA Region Genetics in Immune-mediated Diseases Stephen Hauser
  Genome-wide association studies: a new window into immune-mediated diseases. Ramnik J Xavier, John D,Rioux HLA Region Genetics in Immune-mediated Diseases Stephen Hauser
  Risk alleles for multiple sclerosis identified by a genomewide study. Ramnik J Xavier, John D,Rioux HLA Region Genetics in Immune-mediated Diseases Stephen Hauser
  Role for Msh5 in the regulation of Ig class switch recombination Hideharu Sekine, Ricardo C. Ferreira, Qiang Pan-Hammarstrom, Robert R. Graham, Beth Ziemba, Sandra S. de Vries, Jiabin Liu, Keli Hippen, Thearith Koeuth, Ward Ortmann, Akiko Iwahori, Margaret K. Elliott, Steven Offer, Cara Skon, Likun Du, Jill Novitzke, Annette T. Lee, Nianxi Zhao, Joshua D. Tompkins, David Altshuler, Peter K. Gregersen, Charlotte Cunningham-Rundles, Reuben S. Harris, Chengtao Her, David L. Nelson, Lennart Hammarstrom, Gary S. Gilkeson, and Timothy W. Behrens HLA Region Genetics in Immune-mediated Diseases Stephen Hauser
  Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus. Graham DS, Graham RR, Manku H, Wong AK, Whittaker JC, Gaffney PM, Moser KL, Rioux JD, Altshuler D, Behrens TW, Vyse TJ. HLA Region Genetics in Immune-mediated Diseases Stephen Hauser
HHSN266200400076C Ontology development for biological systems: Immunology Alexander D. Diehl, Jamie A. Lee, Richard H. Scheuermann, and Judith A. Blake Bioinformatics Integration Support Contract Richard H. Scheuermann
  Components of the antigen processing and presentation pathway revealed by gene expression microarray analysis following B cell antigen receptor(BCR)stimulation Jamie A. Lee, Robert S Sinkovits, Dennis Mock, Eva L Rab, Jennifer Cai, Pen Yang, Brian Saunders, Robert C Hsueh, Sangdun Choi, Shankar Subramaniam, Richard H Scheuermann, and in collaboration with the Alliance for Cellular Signaling Bioinformatics Integration Support Contract Richard H. Scheuermann
  A distribution free summarization method for Affymetrix Genechip arrays Zhongxue Chen, Monnie McGee, Qingzhong Liu and Richard H.Scheuermann Bioinformatics Integration Support Contract Richard H. Scheuermann
  Ethical and Practical Issues Associated with Aggregating Databases David R. Karp, Shelly Carlin, Robert Cook-Deegan, Daniel E. Ford, Gail Geller, David N. Glass, Hank Greely, Joel Guthridge, Jeffrey Kahn, Richard Kaslow, Cheryl Kraft, Kathleen MacQueen, Bradley Malin, Richard H.Scheuermann, Jeremy Sugarman Bioinformatics Integration Support Contract Richard H. Scheuermann
  MIFlowCyt: the minimum information about a Flow Cytometry Experiment. Lee JA, Spidlen J, Boyce K, Cai J, Crosbie N, Dalphin M, Furlong J, Gasparetto M, Goldberg M, Goralczyk EM, Hyun B, Jansen K, Kollmann T, Kong M, Leif R, McWeeney S, Moloshok TD, Moore W, Nolan G, Nolan J, Nikolich-Zugich J, Parrish D, Purcell B, Qian Y, Selvaraj B, Smith C, Tchuvatkina O, Wertheimer A, Wilkinson P, Wilson C, Wood J, Zigon R; International Society for Advancement of Cytometry Data Standards Task Force, Scheuermann RH, Brinkman RR Bioinformatics Integration Support Contract Richard H. Scheuermann
  FuGEFlow: data model and markup language for flow cytometry Yu Qian, Olga Tchuvatkina, Josef Spidlen, Peter Wilkinson, Maura Gasparetto, Andrew R Jones, Frank J Manion, Richard H Scheuermann1, Rafick-Pierre Sekaly and Ryan R Brinkman Bioinformatics Integration Support Contract Richard H. Scheuermann
  Technical and Policy Approaches to Balancing Patient Privacy and Data Sharing in Clinical and Translational Research Bradley Malin, David Karp and Richard H. Scheuermann Bioinformatics Integration Support Contract Richard H. Scheuermann
  An Ontology-Based Framework for Clinical Research Databases Megan Kong, Carl Dahlke, Diane Xiang, David Karp, Richard H. Scheuermann Bioinformatics Integration Support Contract Richard H. Scheuermann
  Sequence Feature Variant Type (SFVT) Analysis of the HLA Genetic Association in Juvenile Idiopathic Arthritis Glenys Thomson, Nishanth Marthandan, Jill A. Hollenbach, Steven J. Mack, Henry A. Erlich, Richard M. Single, Matthew J. Waller, Steven G.E. Marsh, Paula A. Guidry, David R. Karp, Richard H. Scheuermann, Susan D. Thompson, David N. Glass and Wolfgang Helmberg Bioinformatics Integration Support Contract Richard H. Scheuermann
  FuGEFlow: data model and markup language for flow cytometry Yu Qian, Olga Tchuvatkina, Joseph Spidlen, Peter Wilkinson, Maura Garparetto, Andrew R. Jones, Frank J. Manion, Richard H. Scheuermann, Rafick-Pierre Sekaly, and Ryan R. Brinkman Bioinformatics Integration Support Contract Richard H. Scheuermann
  FuGEFlow: data model and markup language for flow cytometry Yu Qian, Olga Tchuvatkina, Joseph Spidlen, Peter Wilkinson, Maura Garparetto, Andrew R. Jones, Frank J. Manion, Richard H. Scheuermann, Rafick-Pierre Sekaly, and Ryan R. Brinkman Bioinformatics Integration Support Contract Richard H. Scheuermann
  A Distribution-Free Convolution Model for Background Correction of Oligonucleotide Microarray Data Zhongxue Chen, Monnie McGee, Qingzhong Liu, Megan Kong, Youping Deng and Richard H. Scheuermann Bioinformatics Integration Support Contract Richard H. Scheuermann
  Toward an Ontological Treatment of Disease and Diagnosis Richard H. Scheuermann, Werner Ceusters and Barry Smith Bioinformatics Integration Support Contract Richard H. Scheuermann
  An improved ontological representation of dendritic cells as a paradigm for all cell types Anna M. Masci, Cecilia N. Arighi, Alexander D. Diehl, Anne E. Lieberman, Chris Mungall, Richard H. Scheuermann, Barry Smith and Lindsay G. Cowell Bioinformatics Integration Support Contract Richard H. Scheuermann
  An improved ontological representation of dendritic cells as a paradigm for all cell types Anna M. Masci, Cecilia N. Arighi, Alexander D. Diehl, Anne E. Lieberman, Chris Mungall, Richard H. Scheuermann, Barry Smith and Lindsay G. Cowell Bioinformatics Integration Support Contract Richard H. Scheuermann
  Core and periphery structures in protein interaction networks Feng Luo, Bo Li, Xiu-Feng Wan and Richard H. Scheuermann Bioinformatics Integration Support Contract Richard H. Scheuermann
  Ontology-based Knowledge Representation of Experiment Metadata in Biological Data Mining Richard H. Scheuermann, Megan Kong, Carl Dahlke, Jennifer Cai, Jamie Lee, Yu Qian, Burke Squires, Patrick Dunn, Jeff Wiser, Herb Hagler, Barry Smith and David Karp Bioinformatics Integration Support Contract Richard H. Scheuermann
  Ontology-based Knowledge Representation of Experiment Metadata in Biological Data Mining Megan Kong, Elizabeth McClellan, Richard H. Scheuermann and Monnie McGee Bioinformatics Integration Support Contract Richard H. Scheuermann
NO1-AI-50023* Induction of Antigen-Specific Immunity in Human Neonates and Infants Wilson C, Kollmann T Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Christopher Wilson
  Polychromatic flow cytometric high-throughput assay to analyze the innate immune response to Toll-like receptor stimulation. Jansen K, Blimkie D, Furlong J, Hajjar A, Rein-Weston A, Crabtree J, Reikie B, Wilson C, Kollmann T. Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Christopher Wilson
NO1-AI-50025* Rapid cloning of high-affinity human monoclonal antibodies against influenza virus Jens Wrammert, Kenneth Smith, Joe Miller, William A. Langley, Kenneth Kokko, Christian Larsen, Nai-Ying Zheng, Israel Mays, Lori Garman, Christina Helms, Judith James, Gillian M. Air, J. Donald Capra, Rafi Ahmed & Patrick C. Wilson Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Chris Larsen
NO1-AI-50026* Rapid cloning of high-affinity human monoclonal antibodies against influenza virus Jens Wrammert, Kenneth Smith, Joe Miller, William A. Langley, Kenneth Kokko, Christian Larsen, Nai-Ying Zheng, Israel Mays, Lori Garman, Christina Helms, Judith James, Gillian M. Air, J. Donald Capra, Rafi Ahmed & Patrick C. Wilson Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Linda F. Thompson
NO1-AI-50027* Sultam Thiourea Inhibition of West Nile Virus Eric Barklis, Amelia Still, Mohammad I. Sabri, Alec J. Hirsch, Janko Nikolich-Zugich, James Brien, Tenzin Choesang Dhenub, Isabel Scholz, and Ayna Alfadhli Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Janko Nikolich-Zugich
  Protective capacity and epitope specificity of CD8+ T cells responding to lethal West Nile virus infection James D. Brien, Jennifer L. Uhrlaub, Janko Nikolich-ugich
Vaccine and Gene Therapy Institute and the Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA
Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Janko Nikolich-Zugich
  Protective capacity and epitope specificity of CD8+ T cells responding to lethal West Nile virus infection James D. Brien, Jennifer L. Uhrlaub, Janko Nikolich-ugich
Vaccine and Gene Therapy Institute and the Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA
Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations
  Sultam Thiourea Inhibition of West Nile Virus Barklis, E., A. Still, M.I. Sabri, A.J. Hirsch, J. Nikolich-Zugich, J. Brien, T.C. Dhenub, I. Scholz, and A. Alfadhli. 2007 Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Janko Nikolich-Zugich
  West Nile Virus Infection Activates the Unfolded Protein Response, Leading to CHOP Induction and Apoptosis Guruprasad R. Medigeshi, Alissa M. Lancaster, Alec J. Hirsch, Thomas Briese, W. Ian Lipkin, Victor DeFilippis, Klaus Fr?h, Peter W. Mason, Janko Nikolich-Zugich, and Jay A. Nelson Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Janko Nikolich-Zugich
  West Nile Virus Entry Requires Cholesterol-Rich Membrane Microdomains and Is Independent of {alpha}v {beta}3 Integrin Guruprasad R. Medigeshi, Alec J. Hirsch, Daniel N. Streblow, Janko Nikolich-Zugich, and Jay A. Nelson Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Janko Nikolich-Zugich
  West Nile Virus capsid degradation of claudin proteins disrupts epithelial barrier function. Medigeshi,G.R., A. J. Hirsch, J.D. Brien, J.L. Uhrlaub, P.W. Mason, C.A. Wiley, J. Nikolich-Zugich, and J.A. Nelson. 2009. Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Janko Nikolich-Zugich
  West Nile Virus capsid degradation of claudin proteins disrupts epithelial barrier function. Brien, J.D., J. L. Uhrlaub, A. J. Hirsch, C. A. Wiley and J. Nikolich-Zugich. 2009. Key role of T-cell defects in age-related vulnerability to the West Nile virus Janko Nikolich-Zugich
  West Nile Virus capsid degradation of claudin proteins disrupts epithelial barrier function. Wertheimer, A.M., J. L. Uhrlaub, A. J. Hirsch,G. Medigeshi, J. Sprague, A. Legasse, J. Wilk, C. A. Wiley, P. J. Didier, R. B.Tesh, K.O. Murray, M. K. Axthelm, S. W. Wong, and J. Nikolich-Zugich. PLoS ONE in press. 2010. Immune Response to the West Nile virus in Aged Non-human Primates. Janko Nikolich-Zugich
  West Nile Virus capsid degradation of claudin proteins disrupts epithelial barrier function. Uhrlaub, J.L., J.D. Brien, D.G. Widman, P.W. Mason and J. Nikolich-Zugich. 2010. Repeated in vivo stimulation of T- and B cell responses in old mice generates protective immunity against lethal West Nile virus (WNV) encephalitis. J. Immunol. (in revision) Janko Nikolich-Zugich
  West nile virus-specific CD4 T cells exhibit direct antiviral cytokine secretion and cytotoxicity and are sufficient for antiviral protection. Brien JD, Uhrlaub JL, Nikolich-Zugich J. Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Janko Nikolich-Zugich
NO1-AI-50028* Chromosome-specific and noisy IFNB1 transcription in individual virus-infected human primary dendritic cells. Hu J, Sealfon SC, Hayot F, Jayaprakash C, Kumar M, Pendleton AC, Ganee A, Fernandez-Sesma A, Moran TM, Wetmur JG Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Thomas Moran
  Estrogen inhibits dendritic cell maturation to dsRNA viruses Maria M Escribese, Thomas Kraus, Esther Rhee, Ana Fernandez-Sesma, Carolina B Lopez, and Thomas M Moran Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Thomas Moran
  A Comprehensive Evaluation of Human Plasmacytoid Dendritic Cells Using Small Volumes of Human Blood Hannah Phipps-Yonas, Ke Jiang, Boris Michael Hartmann, Yongchao Ge, Stuart C. Sealfon, Thomas M. Moran. Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Thomas Moran
NO1-AI-50029* Phenotypic and functional heterogeneity of human memory B cells Inaki Sanz, Chungwen Wei, F. Eun-Hyung Lee, and Jennifer Anolik Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Ignacio Sanz
  Cutting edge: anti-tumor necrosis factor therapy in rheumatoid arthritis inhibits memory B lymphocytes via effects on lymphoid germinal centers and follicular dendritic cell networks. Anolik JH, Ravikumar R, Barnard J, Owen T, Almudevar A, Milner EC, Miller CH, Dutcher PO, Hadley JA, Sanz I. Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Ignacio Sanz
NO1-AI-50030* Selective expansion of a subset of exhausted CD8 T cells by alphaPD-L1 blockade. Blackburn SD, Shin H, Freeman GJ, Wherry EJ. Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Hildegund C.J. Ertl
  Two distinct activation states of plasmacytoid dendritic cells induced by influenza virus and CpG 1826 oligonucleotide. Amaya Iparraguirre, John W. Tobias, Scott E. Hensley, Katherine S. Masek, Lois L. Cavanagh, Michael Rendl, Christopher A. Hunter, Hildegund C. Ertl, Ulrich. H. von Andrian and Wolfgang Weninger Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Hildegund C.J. Ertl
  Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection Shawn D Blackburn, Haina Shin, W Nicholas Haining, Tao Zou, Creg J Workman, Antonio Polley, Michael R Betts, Gordon J Freeman, Dario A A Vignali & E John Wherry Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Hildegund C.J. Ertl
NO1-AI-50031* Drak2 Contributes to West Nile Virus Entry into the Brain and Lethal Encephalitis Shuhui Wang, Thomas Welte,Maureen McGargill, Terrence Town, Jesse Thompson, John F. Anderson, Richard A. Flavell, Erol Fikrig, Stephen M. Hedrick and Tian Wang Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Erol Fikrig
  Prevaccine determination of the expression of costimulatory B7 molecules in activated monocytes predicts influenza vaccine responses in young and older adults. van Duin D, Allore HG, Mohanty S, Ginter S, Newman FK, Belshe RB, Medzhitov R, Shaw AC. Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Erol Fikrig
  Abrogation of macrophage migration inhibitory factor decreases West Nile virus lethality by limiting viral neuroinvasion Alvaro Arjona, Harald G. Foellmer, Terrence Town, Lin Leng, Courtney McDonald, Tian Wang, Susan J. Wong, Ruth R. Montgomery, Erol Fikrig and Richard Bucala Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Erol Fikrig
  Age-associated defect in human TLR-1/2 function. van Duin D, Mohanty S, Thomas V, Ginter S, Montgomery RR, Fikrig E, Allore HG, Medzhitov R, Shaw AC Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Erol Fikrig
  West Nile Virus Attenuates Activation of Primary Human Macrophages Kok-Fai Kong, Xiaomei Wang, John F. Anderson, Erol Fikrig, Ruth R. Montgomery Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Erol Fikrig
  West Nile Virus Envelope Protein Inhibits dsRNA-Induced Innate Immune Responses Alvaro Arjona, Michel Ledizet, Karen Anthony, Nathalie Bonaf?, Yorgo Modis, Terrence Town and Erol Fikrig Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Erol Fikrig
  ICAM-1 Participates in the Entry of West Nile Virus into the Central Nervous System Jianfeng Dai, Penghua Wang, Fengwei Bai, Terrence Town, and Erol Fikrig Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Erol Fikrig
  Dysregulation of TLR3 Impairs the Innate Immune Response to West Nile Virus in the Elderly Kok-Fai Kong, Karine Delroux, Xiaomei Wang, Feng Qian, Alvaro Arjona, Stephen E. Malawista, Erol Fikrig, and Ruth R. Montgomery Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Erol Fikrig
  Matrix metalloproteinase 9 facilitates West Nile virus entry into the brain Wang P, Dai J, Bai F, Kong KF, Wong SJ, Montgomery RR, Madri JA, Fikrig E. Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Erol Fikrig
  RNA interference screen for human genes associated with West Nile virus infection Manoj N. Krishnan, Aylwin Ng, Bindu Sukumaran, Felicia D. Gilfoy, Pradeep D. Uchil, Hameeda Sultana, Abraham L. Brass, Rachel Adametz, Melody Tsui, Feng Qian, Ruth R. Montgomery, Sima Lev, Peter W. Mason, Raymond A. Koski, Stephen J. Elledge, Ramnik J. Xavier, Herve Agaisse & Erol Fikrig Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Erol Fikrig
NO1-AI-50032* Influenza Seasonality: Underlying Causes and Modeling Theories Eric Lofgren, N. H. Fefferman, Y. N. Naumov, J. Gorski, and E. N. Naumova Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Jack Gorski
  Regional Differences in Estimation of Influenza Burden in the Elderly: Does Choice of Population Denominator Matter? Cohen, Steven A. and Naumova, Elena N. Immune Function and Biodefense in Children, Elderly, and Immunocompromised Populations Jack Gorski

Sponsored by: